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  "Description": "Converts legacy microscopy video formats (H.264/H.265,\nAVI/MJPEG, TIFF stacks) to the modern 'AV1' codec with minimal\nquality loss. Typical use cases include compressing large TIFF\nstacks from confocal microscopy and time-lapse experiments from\nhundreds of gigabytes to manageable sizes, re-encoding MP4\nfiles exported from 'CellProfiler', 'ImageJ'/'Fiji', and\nmicroscope software with approximately 2x better compression at\nthe same visual quality, and converting legacy AVI (MJPEG) and\nH.265 recordings to a single patent-free format suited for\nlong-term archival. Automatically selects the best available\nbackend: GPU hardware acceleration via 'Vulkan'\n'VK_KHR_VIDEO_ENCODE_AV1' or 'VAAPI' (tested on AMD RDNA4;\nbundled headers, builds with any 'Vulkan' SDK >= 1.3.275), with\nautomatic fallback to CPU encoding through 'FFmpeg' and\n'SVT-AV1'. User controls quality via a single CRF parameter;\neach backend adapts automatically (CPU and Vulkan use CRF\ndirectly, VAAPI targets 55 percent of input bitrate). TIFF\nstacks use near-lossless CRF 5 by default, with optional\nproportional scaling via tiff_scale (multiplier or bounding\nbox, aspect ratio always preserved). Small frames are\nautomatically scaled up to meet hardware encoder minimums.\nAudio tracks are preserved automatically. Provides a simple R\nAPI for batch conversion of entire experiment folders.",
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      "title": "AV1R: 'AV1' Video Encoding for Biological Microscopy Data",
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        "AV1R"
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